Liberated Christians
PO Box 55045, Phoenix AZ 85078-5045
Promoting Intimacy and Other-Centered Sexuality
COPYRIGHTED 1999 ALL RIGHTS RESERVED - MAY BE
REPRINTED OR QUOTED FROM ONLY IF CREDIT IS GIVEN LIBERATED CHRISTIANS, MAILING ADDRESS IS
SHOWN AND WE ARE SENT A COPY OF PUBLICATION.
Why 8 Times Higher AIDS rates in
Blacks vs. Whites?
The CDC data (See http://www.libchrist.com/std/98NewRpt.html)
shows we are in a five year decline in numbers of new cases and it is clear that HIV is
very rare in non IV drug using heterosexual males since HIV is so very difficult for males
to get from heterosexual sex, but why is HIV so racist? Why is AIDS not an Equal
Opportunity Disease?
Here is one possible answer: Genetics
According to genetic research Caucasians have a gene that obliterates the HIV receptor on
lumphoid cells, leading to strong resistance against HIV and AIDS. Africans have no such
gene.
See The American Journal of Human Genetics
Volume 62 Number 6 June 1998 article at
http://www.journals.uchicago.edu/AJHG/journal/issues/v62n6/970785/970785.html
Summary from article:
The CCR5-32 deletion obliterates the CCR5 chemokine and the human immunodeficiency virus
(HIV)1 coreceptor on lymphoid cells, leading to strong resistance against HIV-1 infection
and AIDS. A genotype survey of 4,166 individuals revealed a cline of CCR5-32 allele
frequencies of 0%-14% across Eurasia, whereas the variant is absent among native African,
American Indian, and East Asian ethnic groups. Haplotype analysis of 192 Caucasian
chromosomes revealed strong linkage disequilibrium between CCR5 and two microsatellite
loci. By use of coalescence theory to interpret modern haplotype genealogy, we estimate
the origin of the CCR5-32containing ancestral haplotype to be 700 years ago, with an
estimated range of 275-1,875 years. The geographic cline of CCR5-32 frequencies and its
recent emergence are consistent with a historic strong selective event (e.g., an epidemic
of a pathogen that, like HIV-1, utilizes CCR5), driving its frequency upward in ancestral
Caucasian populations.
The data reported here and elsewhere (Ansari-Lari et al. 1997; Carrington et al. 1997;
Martinson et al. 1997; O'Brien and Dean 1997; Libert et al. 1998) provide indirect but
persuasive evidence for the recent unique occurrence of a deletion mutation in the CCR5
locus that mediates host response to HIV. The CCR5-32 allele, which leads to abolishment
of the CCR5 function, occurs exclusively among Caucasians and describes a north-to-south
geographic cline with a high frequency of 14% among Swedes to 5% among Mediterranean
peoples to 0% among Saudi and East Asian (and article later states none found in African)
populations. The CCR5-32 allele is retained in a 0.9-cM haplotype on chromosome 3 that has
persisted in linkage disequilibrium in human populations for 700 years.
Back To Home Page
Copyright © 1999, Liberated
Christians, Inc.
All Rights Reserved.
E-MAIL: dave@davephx.com